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Hormone therapy for transgender or gender variant individuals, also known as cross-sex hormone therapy, is a form of hormone therapy in which sex hormones and other hormonal medications are administered for the purpose of closely aligning one’s gender expression with one’s gender identity.

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Transfemale/Non-binary transfeminine:
  • Softer skin, less oily
  • Softening/feminising soft tissue of the face
  • Development of breast tissue
  • Slower hair growth
  • Feminisation of body shape – fat redistribution
  • Probably reduced libido
  • Psychological changes include, more emotional possibly tearful, more calm and at peace with one’s true gender identity instilling confidence
Transmale/Non-binary transmasculine:
  • Voice deepens
  • Increase muscle mass
  • Growth of facial and body hair
  • Oily, coarse skin, possibly acne
  • Clitoral growth
  • Increased libido
  • Increased appetite


Hormone therapy has been shown unquestionably to have positive physical and psychological effects on the transitioning individual. It can provide significant comfort to patients who do not want to make a social gender role transition or undergo surgery.

Hormone therapy at LTC is prescribed on an individualised basis depending on a patient’s goals, the risk/benefit ratio of medication, consideration of other medical conditions and social and economic issues.

Frequently Asked Questions

  • How much does it cost?

    From 1st September 2020 we are introducing a direct debit scheme for all new patients.

    The fees for the treatment plan are:

    Upfront Fee: £150

    Year one (monthly x 11 months): £50

    Year two (monthly x 12 months): £30

    Total of Treatment Plan: £1,060 For historic patients who commenced hormone therapy with us before 1st September 2020, pay as you go is still available and costs £150 per follow up appointment. For more information on what the service includes, click here

  • How do I prepare for my consultation?

    1. Ensure you have a psychological assessment with a diagnosis of gender dysphoria/incongruence.
    2. Complete our digital registration form – this will be sent to you once your appointment is confirmed.
    3. Organise the recommended blood tests with your GP practice or private provider. We can suggest The Doctors Laboratory, MediChecks and DocTap
    NB: if you choose MediChecks we are unable to accept finger prick tests.
  • What happens at the consultation?

    The initial consultation takes approximately one and half hours. We will discuss your gender identity, social history, medical history and you will undergo a physical examination to include, inbody analysis, abdominal examination, chest examination (optional), blood pressure, weight and height. Occasionally we can organise the history taking part of your initial consultation via zoom, then your face to face in clinic at a later date. This enables you to complete your blood tests, fertility preservation and any other investigations prior to your Clinic appointment and you will have a second opportunity to discuss any queries which may arise.
  • What happens after my consultation?

    After the consultation, our specialist nurses will issue a medical letter and shared care guidance to your GP. This will ask your GP to continue your prescriptions as recommended by our specialist nurses and/or endocrinologist. You must be reviewed every 6 months for a minimum of 2 years by our specialist nurses to ensure there are no complications following commencement of hormone therapy. It is vital that you attend your follow-up appointments so that we can review your blood levels and ensure your safe progress while on hormone therapy. Failure to attend follow up appointments will unfortunately result in your discharge from LTC as we cannot be responsible for your care unless we can monitor it safely and in your best interest, we will then notify your GP. If and when your care is taken over by an NHS gender identity clinic, we will notify you and your GP of your discharge from our service, unless you decide to remain under our care.
  • What happens if my GP refuses to share care?

    If your GP refuses to share care we will provide you with one free of charge prescription while you attempt to locate a GP who will be happy to share care. If you are unable to find a GP to agree to share care, we can continue to prescribe for you and monitor your progress. This will result in additional costs to you as you will need to purchase private prescriptions at a cost of £50 each.
  • What is included in the payment plan?

    1. All communication with your GP.
    2. Updated medical letters if required when blood results are reviewed, and any adjustments are made to your prescription.
    Also included:
    1. Letter in support of your legal change of name on all documents.
    2. Letter in support of your application for a Gender Recognition Certificate.
  • What is not included?

    Your psychological assessment is not included, you would need to arrange this yourself, however, we will provide contact details of the Psychiatrists and Gender Specialist Psychologists who work closely with The London Transgender Clinic.

    LTC is not a licensed dispensary, therefore, we advise that you take your private prescription to your local pharmacy.

  • What if I discontinue my treatment?

    If you discharge yourself within Year 1, you will be required to continue your payment plan until the end of Year 1 or pay off the remaining amount through a one-off payment. We will then cancel your plan for Year 2. If you discharge yourself within Year 2, you will be required to pay the full remaining amount of the treatment plan, either by continuing your payment plan or a one-off payment.

  • What if I cancel the plan or miss a payment?

    If you miss a payment or cancel your plan without notifying us first, 3 reminders will be sent to pay the outstanding balance. In the event you do not pay the outstanding balance, unfortunately, we will have to discharge you from our care and inform your GP in writing. Any outstanding payments will then be collected by our financial and legal teams.

Related Videos to View

“Had a great experience!!”

5 5 Star Rating Written onDecember 13, 2018 Had a great experience in my initial appointments to get myself started on hormone therapy! 🙂 Very concise and throughout consultations, happy to contact my GP several times afterwards. I will be going in to see Mary after I’ve increased my dosage, more than happy with all the help I’ve gotten from them.  

by Tuomas


Alternative Procedures

  We support and endorse the Guidelines for the Standards of Care for transgender, trans-individuals set out by the World Professional Association for Transgender Health (WPATH).

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