Hormone therapy for transgender or gender variant individuals, also known as cross-sex hormone therapy, is a form of hormone therapy in which sex hormones and other hormonal medications are administered for the purpose of closely aligning one’s gender expression with one’s gender identity.

Make An Enquiry


Hormone therapy has been shown unquestionably to have positive physical and psychological effects on the transitioning individual. It can provide significant comfort to patients who do not want to make a social gender role transition or undergo surgery. Hormone therapy at LTC is prescribed on an individualised basis depending on a patient’s goals, the risk/benefit ratio of medication, consideration of other medical conditions, and social and economic issues.


STEP 1 – Make an enquiry

Register your interest by selecting “Make an Enquiry” and filling in your details.

STEP 2 – Retrieve a referral from a gender psychologist / psychiatrist

Once you complete step 1 we can provide you with a list of available clinicians for you to contact and arrange this, however, it is completely up to you which gender psychologist / psychiatrist you would like to see.

Please arrange this appointment directly with the gender psychologist / psychiatrist. Unfortunately, we cannot do this for you.

STEP 3 – Complete and return your medical forms

Once you see your gender psychologist / psychiatrist, they will send us your referral letter. Make sure you tell them you’d like to be seen at LTC and you’re happy for them to send the referral to us.

Once we receive this, we will send you several essential forms to read and sign. Please read these carefully, sign, and return to us as soon as possible. Any delays prevent us from scheduling your appointment.

STEP 4 – Complete your blood tests

Before you have your first appointment with our hormone prescriber you will need to provide up to date blood tests taken within 6 months of your appointment. Please complete these and send the results to us.

For the full list of blood tests see our FAQ “What are the Essential Blood Tests?”.

To find out where you can have these done, see our FAQ “Where can I go to get my blood tests done?”. Failure to provide these means we cannot schedule your appointment.

STEP 5 – Schedule an appointment

Once we have received the essential forms and your blood results, we will call you to schedule an appointment date.

For pricing and appointment information see our FAQs below.

STEP 6 – Attend your appointment

All there is left to do now is attend your first appointment!

Your first appointment will take place via Zoom, with a face to face follow up approximately 4 weeks later when, if no contra-indications are identified, you will be provided with a prescription to commence hormone therapy.

Frequently Asked Questions

  • What changes can I expect with transfemale/non-binary transfeminine hormone therapy?

    • Softer skin, less oily
    • Softening/feminising soft tissue of the face
    • Development of breast tissue
    • Slower hair growth
    • Feminisation of body shape – fat redistribution
    • Probably reduced libido
    • Psychological changes include more emotional possibly tearful, more calm, and at peace with one’s true gender identity instilling confidence
  • What changes can I expect with transfemale/nonbinary transmasculine hormone therapy?

    • Voice deepens
    • Increase muscle mass
    • Growth of facial and body hair
    • Oily, coarse skin, possibly acne
    • Clitoral growth
    • Increased libido
    • Increased appetite
  • Can I start hormones as a non-binary individual?

    We welcome all trans and non-binary individuals who wish to start hormone therapy with the option of microdosing. As with any patient, we require a diagnosis of Gender Dysphoria/Incongruence from a registered psychologist or psychiatrist.

    Find out more about how Cameron (they/he) started their journey with LTC! Watch on Youtube

  • How much does it cost?

    From 1st September 2020, we are introducing a direct debit scheme subscription and payment plan for all new patients.The fees for the treatment plan are:

    • Upfront Fee: £200
    • Year one (monthly x 11 months): £59
    • Year two (monthly x 12 months): £39

    For more information on our fees and what the service includes, read our patient guide

    For historic patients who commenced hormone therapy with us before 1st September 2020, pay as you go is still available and costs £175 per follow-up appointment.

  • How do I prepare for my consultation?

    1. Retrieve a gender specialist psychological or psychiatric assessment confirming your gender dysphoria/incongruence and suitability to start hormone therapy.
    2. Complete our essential digital registration forms. These will be sent when we receive your referral.
    3. Organise the essential blood tests with your GP practice or private provider. We can suggest MediChecks. To arrange your blood tests with Medichecks, you can call us on 0207 487 0910 and we can arrange this for you.

    NB: if you choose MediChecks we are unable to accept finger-prick tests.

  • What are the essential blood tests?


    • Liver Function Test (LFT)
    • Full Blood Count (FBC)
    • Fasting Lipid Profile
    • Fasting Glucose
    • Serum Testosterone
    • Serum Oestradiol
    • Serum Prolactin
    • Follicle-Stimulating Hormone (FSH)
    • Luteinising Hormone (LH)
    • SHBG
    • U+E


    • Liver Function Test (LFT)
    • LH
    • Full Blood Count (FBC)
    • Fasting Lipid Profile
    • Fasting Glucose
    • FSH
    • Serum Testosterone
    • Serum Oestradiol
    • Serum Prolactin
    • U+E
    • SHBG
    • Prostate-Specific Antigen (if >50 years of age)
  • What happens at the consultation?

    At your initial videolink consultation, your prescriber and you will discuss your gender identity, social, and medical history. This usually takes around 1 hour.

    Approximately 4 weeks later, you will have a face-to-face consultation where you will undergo a physical examination to include, InBody analysis, blood pressure, weight, and height. Again, this usually takes around 1 hour.

    The gap between the two appointments enables you to complete additional blood tests, fertility preservation, and any other investigations where a need has been identified at the first consultation. It will also give you a second opportunity to discuss any queries which may arise.

  • Where can I get my blood tests?

    If you do not currently have any or all of the essential blood test results to hand – dated within the last 6 months – please contact your GP to arrange a blood test.

    Alternatively, if your GP is unable to arrange these for you, we can suggest MediChecks. To arrange your blood tests with Medicheck, please call us on 0207 487 0910 and we can schedule this for you.

    Please note if you arrange these yourself, we are unable to accept finger-prick tests.

  • What happens after my consultation?

    After your face-to-face consultation, our specialist nurses will issue a medical letter and shared care guidance to your GP. This will ask your GP to continue your prescriptions as recommended by our specialist nurses and/or endocrinologist.

    You must be reviewed every 6 months for a minimum of 2 years by our specialist nurses to monitor your progress and assess any side effects that may require adjustment of your hormone therapy. It is vital that you attend your follow-up appointments so that we can review your blood levels and ensure your safe progress while on hormone therapy. Failure to attend follow-up appointments will, unfortunately, result in your discharge from LTC as we cannot be responsible for your care unless we can monitor it safely and in your best interest, we will then notify your GP.

    If and when your care is taken over by an NHS gender identity clinic we will notify you and your GP of your discharge from our service, unless you decide to remain under our care.

  • What happens if my GP refuses to share care?

    If your GP refuses to share care and you are on our monthly payment plan, we will provide you with prescriptions as part of your service package while you attempt to locate a GP who will be happy to share care.

    If you are not on our monthly payment plan, you can purchase private prescriptions at a cost of £50 while you attempt to locate a GP who will be happy to share care.

  • What is included in the payment plan?

    1. All communication with your GP.
    2. Updated medical letters if required when blood results are reviewed, and any adjustments are made to your prescription.
    3. All prescriptions as required
    Also included:
    1. Letter in support of your legal change of name on all documents.
    2. Letter in support of your application for a Gender Recognition Certificate.
  • What is not included?

    Your psychological assessment is not included, you would need to arrange this yourself, however, we will provide contact details of the Psychiatrists and Gender Specialist Psychologists who work closely with The London Transgender Clinic. LTC is not a licensed dispensary, therefore, we advise that you take your private prescription to your local pharmacy.

  • What if I discontinue my treatment?

    If you discharge yourself within Year 1, you will be required to continue your payment plan until the end of Year 1 or pay off the remaining amount through a one-off payment. We will then cancel your plan for Year 2. If you discharge yourself within Year 2, you will be required to pay the full remaining amount of the treatment plan, either by continuing your payment plan or a one-off payment.

  • What if I cancel the plan or miss a payment?

    If you miss a payment or cancel your plan without notifying us first, 3 reminders will be sent to pay the outstanding balance. In the event you do not pay the outstanding balance, unfortunately, we will have to discharge you from our care and inform your GP in writing. Any outstanding payments will then be collected by our financial and legal teams.

  • How can I connect with other patients?

    If you are an existing patient and you would like to connect with other people on the same journey to exchange experiences and opinions, you can join one of our Facebook groups.

    If you are a trans male or trans-masculine non-binary patient, you can join this group.

    If you are a trans female or trans-feminine non-binary patient, you can join this group.

Related Videos to View

“Had a great experience!!”

5 5 Star Rating
Written onDecember 13, 2018

Had a great experience in my initial appointments to get myself started on hormone therapy! 🙂

Very concise and throughout consultations, happy to contact my GP several times afterwards.

I will be going in to see Mary after I’ve increased my dosage, more than happy with all the help I’ve gotten from them.


by Tuomas


We support and endorse the Guidelines for the Standards of Care for transgender, trans-individuals set out by the World Professional Association for Transgender Health (WPATH).World Professional Association for Transgender Health logo


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